A novel recirculating flow-perfusion bioreactor for periosteal chondrogenesis
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چکیده
منابع مشابه
A Novel Flow-Perfusion Bioreactor Supports 3D Dynamic Cell Culture
BACKGROUND Bone engineering requires thicker three-dimensional constructs than the maximum thickness supported by standard cell-culture techniques (2 mm). A flow-perfusion bioreactor was developed to provide chemotransportation to thick (6 mm) scaffolds. METHODS Polyurethane scaffolds, seeded with murine preosteoblasts, were loaded into a novel bioreactor. Control scaffolds remained in static...
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Tissue engineering has been developed as a new approach in regenerating tissues and organs using cells and scaffolds. An important element in successful tissue engineering in vitro is a suitable bioreactor system (Freed and Vunjak-Novakovic 1997). In general, some types of bioreactors have been used for cell culture on polymer scaffolds, namely spinner flasks, rotating vessels, and perfusion sy...
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Several different bioreactors have been investigated for tissue-engineering applications. Among these bioreactors are the spinner flask and the rotating wall vessel reactor. In addition, a new type of culture system has been developed and investigated, the flow perfusion culture bioreactor. Flow perfusion culture offers several advantages, notably the ability to mitigate both external and inter...
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ژورنال
عنوان ژورنال: International Orthopaedics
سال: 2011
ISSN: 0341-2695,1432-5195
DOI: 10.1007/s00264-011-1291-x